Over the course of Hugh Laurie's character, Dr. Gregory House. The protagonist is a genius (and cynical curmudgeon) who leads a team of doctors in the diagnostic medicine department at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. Together, they take on strange and unusual medical cases without official diagnoses every episode and try to solve them.

House received 13 Emmy nominations throughout its eight-year run, including four Outstanding Drama Series nods and six Outstanding Lead Actor in a Drama Series nominations for Hugh Laurie. The show ultimately won two Emmys — Outstanding Writing for a Drama Series for "Three Stories" by David Shore and Outstanding Directing in a Drama Series for Greg Yaitanes' work on "House's Head."

Some episodes of House somewhat stray from the norm, but they all typically feature some kind of mystery. The show's investigative format allows the writers to continuously surprise the audience, whether with reveals concerning the patients or the main/ing characters themselves. However, one of House's most shocking and unforgettable moments arises during the two-part season 4 finale, and it's a scene that haunts me to this day, 17 years after the episode's premiere.

The Amber Reveal In "House's Head" Is House's Most Heartbreaking Moment

The Shocking Twist Is Revealed In The Best (Saddest) Way

House season 4, episode 15, "House's Head," begins with House realizing he was in a bus crash that resulted in a concussion and post-traumatic retrograde amnesia. Essentially, House loses his memory of everything that happened from just before the accident to the few hours after it. So, he spends the hour trying to put the pieces back together. The one thing that Hugh Laurie's character can is seeing someone on the bus who he knows will die. By the end of the stressful House episode, House and the audience are shocked to learn that Dr. Amber Volakis is that person.

House hallucinates a woman, played by Ivana Milicevic, who he knows wasn't in the accident. However, she's the key to all the answers. In House's imagination, she gives him clues regarding the dying person's identity and continuously asks him what her necklace is made of. House dismisses her query at first, but then he horrifyingly realizes why she is quizzing him about her jewelry. Her necklace is fashioned from amber, and House's memories come flooding back. Amber is the person he was with on the bus, and she is the one who is dying in the two-part House season 4 finale.

No Other Moment In House Ever Beat The Shock Of The Bus Scene Reveal

The Scene Is More Shocking Than Any Other Moment In House

While watching the remarkable House episode, not many would guess that Amber is the one House is trying to find. Consequently, the reveal at the hour's end is more jaw-dropping than any other moment in the Fox medical drama TV show. The two-part House season 4 finale finally unveiling the answer via the amber necklace is also spine-chilling and ingenious on the writers' behalf.

Amber, one of the doctors in House's fellowship program and Dr. James Wilson's girlfriend, wasn't the most beloved character in House by any means. Nevertheless, the season 4 episode revealing that she was the one in the bus crash is wholly surprising and devastating all the same, especially because she ultimately dies. House goes on to produce many other unforgettable scenes and episodes after season 4. However, nothing could ever come close to the effect the Amber twist has on the audience.

"House's Head" And "Wilson's Heart" Are Arguably The Show's Best Episodes

Nothing Comes Close To House's 2-Part Season 4 Finale

Many shows reach their peaks in their first seasons, but that wasn't the case for Hugh Laurie's series. Some of House's best episodes come after season 1, and the two-part season 4 finale ("House's Head" and "Wilson's Heart") arguably sits at the top of the list. The two episodes are tied for the medical drama's highest IMDb score (9.7/10), after all. "House's Head" (which won an Emmy) and "Wilson's Heart" are simply two of the most well-made episodes in network TV history, and anyone who has watched these hours of House will never be able to forget them.

Source: IMDb